nicolas Leveziel (250x223)

EQUIPE de rattachement : Equipe 1 (Afsaneh Gaillard)

NOM Prénom : LEVEZIEL Nicolas

Statut (date de début-fin prévue si CDD): PU-PH

Adresse :

Service d’ophtalmologie

CHU de Poitiers

2 rue de la Miléterie

86021 Poitiers

Tél : 0549444182

e-mail :nicolas.leveziel@chu-poitiers.fr

Publications (toutes les marquantes, y compris avant 2012)

1: Holz FG, Tufail A, Leveziel N, Lai TY, Lanzetta P, Wong TY, Yu HG, Chen YX,

Heinrichs N, Pilz S, Ohno-Matsui K; RADIANCE Study Group. Ranibizumab in Myopic

Choroidal Neovascularization: A Subgroup Analysis by Ethnicity, Age, and Ocular

Characteristics in RADIANCE. Ophthalmologica. 2016 Jun 7. [Epub ahead of print]

PubMed PMID: 27270597.

2: Bourgeois N, Chavant F, Lafay-Chebassier C, Leveziel N, Pérault-Pochat MC.

[Drugs and retinal disorders: A case/non-case study in the French

pharmacovigilance database]. Therapie. 2016 Feb 15. pii: S0040-5957(16)00049-4.

doi: 10.1016/j.therap.2016.02.024. [Epub ahead of print] French. PubMed PMID:


3: Lichtwitz O, Boissonnot M, Mercié M, Ingrand P, Leveziel N. Prevalence of

macular complications associated with high myopia by multimodal imaging. J Fr

Ophtalmol. 2016 Apr;39(4):355-63. doi: 10.1016/j.jfo.2015.11.005. Epub 2016 Mar

  1. PubMed PMID: 27016335.

4: Kostine M, Lichtwitz O, Truchetet ME, Leveziel N. Choroidal osteoma: Bone in

the eye. Joint Bone Spine. 2016 Jul;83(4):454. doi: 10.1016/j.jbspin.2015.07.005.

Epub 2015 Dec 8. PubMed PMID: 26677997.

5: Gaucher D, Chartier C, Cohen SY, Malecaze F, Souied EH, Weber M, Leveziel N.

[High myopic patients: A survey of their history, feelings, beliefs and needs]. J

Fr Ophtalmol. 2016 Jan;39(1):12-9. doi: 10.1016/j.jfo.2015.04.019. Epub 2015 Nov

  1. French. PubMed PMID: 26607101.

6: Matamoros E, Ingrand P, Pelen F, Bentaleb Y, Weber M, Korobelnik JF, Souied E,

Leveziel N. Prevalence of Myopia in France: A Cross-Sectional Analysis. Medicine

(Baltimore). 2015 Nov;94(45):e1976. doi: 10.1097/MD.0000000000001976. PubMed

PMID: 26559276.

7: Matamoros E, Maurel F, Léon N, Solomiac A, Bardoulat I, Joubert M, Hermans M,

Moser E, Le Picard S, Souied EH, Leveziel N. Quality of Life in Patients

Suffering from Active Exudative Age-Related Macular Degeneration: The EQUADE

Study. Ophthalmologica. 2015;234(3):151-9. doi: 10.1159/000433448. Epub 2015 Aug

  1. PubMed PMID: 26337381.

8: Leveziel N, Ragot S, Gand E, Lichtwitz O, Halimi JM, Gozlan J, Gourdy P,

Robert MF, Dardari D, Boissonnot M, Roussel R, Piguel X, Dupuy O, Torremocha F,

Saulnier PJ, Maréchaud R, Hadjadj S; DIAB2NEPHROGENE study group. Association

Between Diabetic Macular Edema and Cardiovascular Events in Type 2 Diabetes

Patients: A Multicenter Observational Study. Medicine (Baltimore). 2015

Aug;94(33):e1220. doi: 10.1097/MD.0000000000001220. PubMed PMID: 26287408; PubMed

Central PMCID: PMC4616429.

9: Cazet-Supervielle A, Gozlan J, Cabasson S, Boissonnot M, Manic H, Leveziel N.

Intravitreal Ranibizumab in Daily Clinical Practice for Age-Related Macular

Degeneration: Treatment of Exudative Age-Related Macular Degeneration in Real

Life. Ophthalmologica. 2015;234(1):26-32. doi: 10.1159/000430470. Epub 2015 Jun

  1. PubMed PMID: 26111575.

10: Dossarps D, Bron AM, Koehrer P, Aho-Glélé LS, Creuzot-Garcher C; FRCR net

(FRenCh Retina specialists net). Endophthalmitis After Intravitreal Injections:

Incidence, Presentation, Management, and Visual Outcome. Am J Ophthalmol. 2015

Jul;160(1):17-25.e1. doi: 10.1016/j.ajo.2015.04.013. Epub 2015 Apr 16. PubMed

PMID: 25892127.

11: Lichtwitz O, Leveziel N. Two scleral ectasias in high myopia. JAMA

Ophthalmol. 2015 Mar;133(3):e141980. doi: 10.1001/jamaophthalmol.2014.1980. Epub

2015 Mar 12. PubMed PMID: 25763548.

12: Wong TY, Ohno-Matsui K, Leveziel N, Holz FG, Lai TY, Yu HG, Lanzetta P, Chen

Y, Tufail A. Myopic choroidal neovascularisation: current concepts and update on

clinical management. Br J Ophthalmol. 2015 Mar;99(3):289-96. doi:

10.1136/bjophthalmol-2014-305131. Epub 2014 Jul 1. Review. PubMed PMID: 24990871;

PubMed Central PMCID: PMC4345796.

13: Leveziel N, Pelat T, Watier H, Thullier P, Souied EH. Detection of

antiranibizumab antibodies among patients with exudative age-related macular

degeneration. Ophthalmologica. 2014;232(1):53-6. doi: 10.1159/000360186. Epub

2014 May 20. PubMed PMID: 24854579.

14: Merle BM, Benlian P, Puche N, Bassols A, Delcourt C, Souied EH; Nutritional

AMD Treatment 2 Study Group. Circulating omega-3 Fatty acids and neovascular

age-related macular degeneration. Invest Ophthalmol Vis Sci. 2014 Mar

28;55(3):2010-9. doi: 10.1167/iovs.14-13916. PubMed PMID: 24557349.

15: Pedinielli A, Souied EH, Perrenoud F, Leveziel N, Caillaux V, Querques G. In

vivo visualization of perforating vessels and focal scleral ectasia in

pathological myopia. Invest Ophthalmol Vis Sci. 2013 Nov 19;54(12):7637-43. doi:

10.1167/iovs.13-12981. PubMed PMID: 24194186.

16: Tilleul J, Richard F, Puche N, Zerbib J, Leveziel N, Sahel JA, Cohen SY,

Korobelnik JF, Feingold J, Munnich A, Kaplan J, Rozet JM, Souied EH. Genetic

association study of mitochondrial polymorphisms in neovascular age-related

macular degeneration. Mol Vis. 2013 May 29;19:1132-40. Print 2013. PubMed PMID:

23734082; PubMed Central PMCID: PMC3669531.

17: Puche N, Blanco-Garavito R, Richard F, Leveziel N, Zerbib J, Tilleul J,

Mimoun G, Querques G, Cohen SY, Souied EH. Genetic and environmental factors

associated with reticular pseudodrusen in age-related macular degeneration.

Retina. 2013 May;33(5):998-1004. doi: 10.1097/IAE.0b013e31827b6483. PubMed PMID:


18: Forte R, Querques G, Querques L, Leveziel N, Benhamou N, Souied EH.

Multimodal evaluation of foveal sparing in patients with geographicatrophy due to

age-related macular degeneration. Retina. 2013 Mar;33(3):482-9. doi:

10.1097/IAE.0b013e318276e11e. PubMed PMID: 23400084.

19: Souied EH, Delcourt C, Querques G, Bassols A, Merle B, Zourdani A, Smith T,

Benlian P; Nutritional AMD Treatment 2 Study Group. Oral docosahexaenoic acid in

the prevention of exudative age-related macular degeneration: the Nutritional AMD

Treatment 2 study. Ophthalmology. 2013 Aug;120(8):1619-31. doi:

10.1016/j.ophtha.2013.01.005. Epub 2013 Feb 8. PubMed PMID: 23395546.

20: Leveziel N, Caillaux V, Bastuji-Garin S, Zmuda M, Souied EH. Angiographic and

optical coherence tomography characteristics of recent myopic choroidal

neovascularization. Am J Ophthalmol. 2013 May;155(5):913-9. doi:

10.1016/j.ajo.2012.11.021. Epub 2013 Jan 23. PubMed PMID: 23352343.

Guigui B, Querques G, Leveziel N, Bouakkaz H, Massamba N, Coscas G, Souied

  1. Spectral-domain optical coherence tomography of early onset large colloid

drusen. Retina. 2013 Jul-Aug;33(7):1346-50. doi: 10.1097/IAE.0b013e318283127d.

PubMed PMID: 23348864.

22: Srour M, Querques G, Leveziel N, Zerbib J, Tilleul J, Boulanger-Scemama E,

Souied EH. Intravitreal dexamethasone implant (Ozurdex) for macular edema

secondary to retinitis pigmentosa. Graefes Arch Clin Exp Ophthalmol. 2013

Jun;251(6):1501-6. doi: 10.1007/s00417-012-2249-4. Epub 2012 Dec 29. PubMed PMID:


23: Querques G, Querques L, Leveziel N, Bandello F, Souied EH. Intravitreal

ranibizumab for type 3 choroidal neovascularization complicating adult onset

foveomacular vitelliform dystrophy. J Fr Ophtalmol. 2013 Jan;36(1):e1-4. doi:

10.1016/j.jfo.2012.04.013. Epub 2012 Dec 4. PubMed PMID: 23218864.

24: Tilleul J, Querques G, Canoui-Poitrine F, Leveziel N, Souied EH. Assessment

of a spectral domain OCT segmentation software in a retrospective cohort study of

exudative AMD patients. Ophthalmologica. 2013;229(2):80-5. doi:

10.1159/000342980. Epub 2012 Nov 20. PubMed PMID: 23171503.

25: Fourgeux C, Dugas B, Richard F, Björkhem I, Acar N, Bron AM, Korobelnik JF,

Leveziel N, Zerbib J, Puche N, Creuzot-Garcher CP, Souied E, Bretillon L. Single

nucleotide polymorphism in the cholesterol-24S-hydroxylase (CYP46A1) gene and its

association with CFH and LOC387715 gene polymorphisms in age-related macular

degeneration. Invest Ophthalmol Vis Sci. 2012 Oct 9;53(11):7026-33. doi:

10.1167/iovs.12-9652. PubMed PMID: 22977134.


26: Souied EH, Leveziel N. Toward personalized medicine for age-related macular

degeneration. Am J Ophthalmol. 2012 Sep;154(3):427-8. doi:

10.1016/j.ajo.2012.05.022. PubMed PMID: 22898343.

27: Querques G, Guigui B, Leveziel N, Querques L, Bandello F, Souied EH.

Multimodal morphological and functional characterization of Malattia Leventinese.

Graefes Arch Clin Exp Ophthalmol. 2013 Mar;251(3):705-14. doi:

10.1007/s00417-012-2106-5. Epub 2012 Jul 20. PubMed PMID: 22814526.

28: Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH,

Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA,

Lee AY, Leveziel N, Zack DJ, Campochiaro P, Smith RT, Barile GR, Hogg RE,

Chakravarthy U, Behrens TW, Uitterlinden AG, van Duijn CM, Vingerling JR,

Brantley MA Jr, Baird PN, Klaver CC, Allikmets R, Katsanis N, Graham RR,

Ioannidis JP, Daly MJ, Seddon JM. Heritability and genome-wide association study

to assess genetic differences between advanced age-related macular degeneration

subtypes. Ophthalmology. 2012 Sep;119(9):1874-85. doi:

10.1016/j.ophtha.2012.03.014. Epub 2012 Jun 15. PubMed PMID: 22705344; PubMed

Central PMCID: PMC3899891.

29: Leveziel N, Yu Y, Reynolds R, Tai A, Meng W, Caillaux V, Calvas P, Rosner B,

Malecaze F, Souied EH, Seddon JM. Genetic factors for choroidal

neovascularization associated with high myopia. Invest Ophthalmol Vis Sci. 2012

Jul 27;53(8):5004-9. doi: 10.1167/iovs.12-9538. PubMed PMID: 22678500; PubMed

Central PMCID: PMC3410690.

30: Leveziel N, Lalloum F, Bastuji-Garin S, Binaghi M, Bachir D, Galacteros F,

Souied E. [Sickle-cell retinopathy: Retrospective study of 730 patients followed

in a referral center]. J Fr Ophtalmol. 2012 May;35(5):343-7. doi:

10.1016/j.jfo.2011.10.007. Epub 2012 Apr 1. French. PubMed PMID: 22472104.

31: Dethorey G, Leveziel N, Lalloum F, Forte R, Guigui B, Querques G,

Glacet-Bernard A, Soubrane G, Souied HÉ. [Efficacy of intravitreal injections of

ranibizumab compared to visudyne phototherapy in myopic choroidal

neovascularization associated with high myopia]. J Fr Ophtalmol. 2012

Feb;35(2):106-12. doi: 10.1016/j.jfo.2011.03.028. Epub 2011 Nov 15. French.

PubMed PMID: 22088356.

32: Leveziel N, Bastuji-Garin S, Lalloum F, Querques G, Benlian P, Binaghi M,

Coscas G, Soubrane G, Bachir D, Galactéros F, Souied EH. Clinical and laboratory

factors associated with the severity of proliferative sickle cell retinopathy in

patients with sickle cell hemoglobin C (SC) and homozygous sickle cell (SS)

disease. Medicine (Baltimore). 2011 Nov;90(6):372-8. doi:

10.1097/MD.0b013e3182364cba. PubMed PMID: 22033449.

33: Leveziel N, Tilleul J, Puche N, Zerbib J, Laloum F, Querques G, Souied EH.

Genetic factors associated with age-related macular degeneration.

Ophthalmologica. 2011;226(3):87-102. doi: 10.1159/000328981. Epub 2011 Jul 14.

Review. PubMed PMID: 21757876.

34: Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH,

Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA,

Sobrin L, Evangelou E, Lee PH, Lee AY, Leveziel N, Zack DJ, Campochiaro B,

Campochiaro P, Smith RT, Barile GR, Guymer RH, Hogg R, Chakravarthy U, Robman LD,

Gustafsson O, Sigurdsson H, Ortmann W, Behrens TW, Stefansson K, Uitterlinden AG,

van Duijn CM, Vingerling JR, Klaver CC, Allikmets R, Brantley MA Jr, Baird PN,

Katsanis N, Thorsteinsdottir U, Ioannidis JP, Daly MJ, Graham RR, Seddon JM.

Common variants near FRK/COL10A1 and VEGFA are associated with advanced

age-related macular degeneration. Hum Mol Genet. 2011 Sep 15;20(18):3699-709.

doi: 10.1093/hmg/ddr270. Epub 2011 Jun 10. PubMed PMID: 21665990; PubMed Central

PMCID: PMC3159552.

35: Zerbib J, Puche N, Richard F, Leveziel N, Cohen SY, Korobelnik JF, Sahel J,

Munnich A, Kaplan J, Rozet JM, Souied EH. No association between the T280M

polymorphism of the CX3CR1 gene and exudative AMD. Exp Eye Res. 2011

Oct;93(4):382-6. doi: 10.1016/j.exer.2011.05.005. Epub 2011 May 20. PubMed PMID:


36: Querques G, Guigui B, Leveziel N, Querques L, Coscas G, Soubrane G, Souied

  1. Insights into pathology of cuticular drusen from integrated confocal scanning

laser ophthalmoscopy imaging and corresponding spectral domain optical coherence

tomography. Graefes Arch Clin Exp Ophthalmol. 2011 Nov;249(11):1617-25. doi:

10.1007/s00417-011-1702-0. Epub 2011 May 10. PubMed PMID: 21556939.

37: Querques G, Kuhn D, Massamba N, Leveziel N, Querques L, Souied EH. Perifoveal

exudative vascular anomalous complex. J Fr Ophtalmol. 2011 Oct;34(8):559.e1-4.

doi: 10.1016/j.jfo.2011.03.002. Epub 2011 May 7. PubMed PMID: 21550688.

38: Querques G, Atmani K, Bouzitou-Mfoumou R, Leveziel N, Massamba N, Souied EH.

Preferential hyperacuity perimeter in best vitelliform macular dystrophy. Retina.

2011 May;31(5):959-66. doi: 10.1097/IAE.0b013e3181f441c1. PubMed PMID: 21242858.

39: Querques G, Berboucha E, Leveziel N, Pece A, Souied EH. Preferential

hyperacuity perimeter in assessing responsiveness to ranibizumab therapy for

exudative age-related macular degeneration. Br J Ophthalmol. 2011

Jul;95(7):986-91. doi: 10.1136/bjo.2010.190942. Epub 2010 Dec 22. PubMed PMID:


40: Sobrin L, Reynolds R, Yu Y, Fagerness J, Leveziel N, Bernstein PS, Souied EH,

Daly MJ, Seddon JM. ARMS2/HTRA1 locus can confer differential susceptibility to

the advanced subtypes of age-related macular degeneration. Am J Ophthalmol. 2011

Feb;151(2):345-52.e3. doi: 10.1016/j.ajo.2010.08.015. Epub 2010 Dec 3. PubMed

PMID: 21122828; PubMed Central PMCID: PMC3763907.

  1. Guigui B, Leveziel N, Martinet V, Massamba N, Sterkers M, Coscas G, Souied EH.

Angiography features of early onset drusen. Br J Ophthalmol. 2011

Feb;95(2):238-44. doi: 10.1136/bjo.2009.178400. Epub 2010 Jul 7. PubMed PMID:



Menu principal

Haut de page